Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.

PloS one - 1 Jan 2013

Li Pengfei, Carter Gay, Romero Jacqueline, Gower Kathryn M, Watson James, Patel Niketa A, Cooper Denise R

Abstract excerpt

The development of adipocytes from their progenitor cells requires the action of growth factors signaling to transcription factors to induce the expression of adipogenic proteins leading to the accumulation of lipid droplets, induction of glucose transport, and secretion of adipokines signaling metabolic events throughout the body. Murine 3T3-L1 pre-adipocytes sequentially express all the proteins necessary to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Adipocytes
Share to Adipogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Kinase C

Share to Protein Kinase C beta

Share to Proto-Oncogene Proteins c-akt

Share to Serine-Arginine Splicing Factors

Share to Thiazoles

Source

Open in PubMed Open full text

Identifiers

PMID: 23308182
DOI: 10.1371/journal.pone.0053268
PMCID: PMC3537621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.PMID 23308182Read ↗

STAT3 Is the Master Regulator for the Forming of 3D Spheroids of 3T3-L1 PreadipocytesSemantic proximity Read ↗

Analysis of DYRK1B, PPARG, and CEBPB Expression Patterns in Adipose-Derived Stem Cells from Patients carrying DYRK1B R102C and Healthy Individuals During AdipogenesisSemantic proximity Read ↗

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.Semantic proximity Read ↗

Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytesSemantic proximity Read ↗

Transformer 2β homolog (Drosophila) (TRA2B) regulates protein kinase C δI (PKCδI) splice variant expression during 3T3L1 preadipocyte cell cycle.Semantic proximity Read ↗

Analysis of DYRK1B, PPARG, and CEBPB Expression Patterns in Adipose-Derived Stem Cells from Patients Carrying DYRK1B R102C and Healthy Individuals During AdipogenesisSemantic proximity Read ↗

Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte ProliferationSemantic proximity Read ↗

Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and ObesitySemantic proximity Read ↗

Akt is required for Stat5 activation and mammary differentiationSemantic proximity Read ↗

Cyclin D3 promotes adipogenesis through activation of peroxisome proliferator-activated receptor gamma.Semantic proximity Read ↗

The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes.Semantic proximity Read ↗

Srebf1a is a key regulator of transcriptional control for adipogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.