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Article

Robust cone-mediated signaling persists late into rod photoreceptor degeneration

2022-04-28

Abstract excerpt

Rod photoreceptor degeneration causes deterioration in the morphology and physiology of cone photoreceptors along with changes in retinal circuits. These changes could diminish visual signaling at cone-mediated light levels, thereby limiting the efficacy of treatments such as gene therapy for rescuing normal, cone-mediated vision. However, the impact of progressive rod death on cone-mediated signaling remains uncl...

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Literature Corpus work
62e5c006-aa69-5b09-94f0-362e85dee720
DOI
10.1101/2022.04.27.489758
Open publication

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Robust cone-mediated signaling persists late into rod photoreceptor degenerationDOI 10.1101/2022.04.27.489758
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