Article
In vivo recognition of the fecA3 target promoter by Helicobacter pylori NikR.
Journal of bacteriology - 1 Mar 2011
Romagnoli Simona, Agriesti Francesca, Scarlato Vincenzo
Abstract excerpt
In Helicobacter pylori, the transcriptional regulator HpNikR represses transcription of the fecA3 gene by binding to two adjacent operators spanning a region of almost 80 nucleotides along the fecA3 promoter in a nickel-dependent manner. By employing hydroxyl radical footprinting, we mapped the protected nucleotides within each operator. Three short sequences rich in A and T nucleotides were identified within...
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