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Article

Acid-responsive activity of the Helicobacter pylori metalloregulator NikR

20 Aug 2018

Abstract excerpt

Significance The acid adaptation systems of the pathogen Helicobacter pylori are complex and critical to the survival of this bacterium in the harsh environment of the human stomach. One of the relatively few transcription factors in H. pylori is HpNikR, a metal-responsive protein that controls homeostasis of nickel, an essential nutrient for this organism. In this study, we show that HpNikR also regulates gene...

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PMID: 30126985
DOI: 10.1073/pnas.1808393115

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