Article
NikR Mediates Nickel-Responsive Transcriptional Induction of Urease Expression in<i>Helicobacter pylori</i>
1 Jun 2002
Abstract excerpt
The important human pathogen Helicobacter pylori requires the abundant expression and activity of its urease enzyme for colonization of the gastric mucosa. The transcription, expression, and activity of H. pylori urease were previously demonstrated to be induced by nickel supplementation of growth media. Here it is demonstrated that the HP1338 protein, an ortholog of the Escherichia coli nickel regulatory protein...
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