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Article

A Repeat-Associated Small RNA Controls the Major Virulence Factors of Helicobacter pylori.

Molecular cell - 15 Oct 2020

Eisenbart Sara K, Alzheimer Mona, Pernitzsch Sandy R, Dietrich Sascha, Stahl Stephanie, Sharma Cynthia M

Abstract excerpt

Many bacterial pathogens regulate their virulence genes via phase variation, whereby length-variable simple sequence repeats control the transcription or coding potential of those genes. Here, we have exploited this relationship between DNA structure and physiological function to discover a globally acting small RNA (sRNA) regulator of virulence in the gastric pathogen Helicobacter pylori. Our study reports the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33002424
DOI: 10.1016/j.molcel.2020.09.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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