Article
Germline copy number variations in BRCA1-associated ovarian cancer patients.
Genes, chromosomes & cancer - 1 Mar 2011
Yoshihara Kosuke, Tajima Atsushi, Adachi Sosuke, Quan Jinhua, Sekine Masayuki, Kase Hiroaki, Yahata Tetsuro, Inoue Ituro, Tanaka Kenichi
Abstract excerpt
We investigated characteristics of germline copy number variations (CNV) in BRCA1-associated ovarian cancer patients by comparing them to CNVs present in sporadic ovarian cancer patients. Germline CNVs in 51 BRCA1-associated, 33 sporadic ovarian cancer patients, and 47 healthy women were analyzed by both signal intensity and genotyping data using the Affymetrix Genome-Wide Human SNP Array 6.0. The total number of...
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