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Article

Recurrent copy number alterations in BRCA1-mutated ovarian tumors alter biological pathways.

Human mutation - 1 Dec 2009

Leunen Karin, Gevaert Olivier, Daemen Anneleen, Vanspauwen Vanessa, Michils Geneviève, De Moor Bart, Moerman Philippe, Vergote Ignace, Legius Eric

Abstract excerpt

Array CGH was used to identify recurrent copy number alterations (RCNA) characteristic of either BRCA1-related or sporadic ovarian cancer. After preprocessing, both groups of patients were modeled using a recurrent Hidden Markov Model to detect RCNA. RCNA with a probability higher than 80% were c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19802895
DOI: 10.1002/humu.21135

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19802895-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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