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Article

The p53 mutational spectrum associated with BRCA1 mutant ovarian cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2001

Buller R E, Lallas T A, Shahin M S, Sood A K, Hatterman-Zogg M, Anderson B, Sorosky J I, Kirby P A

Abstract excerpt

PURPOSE: Cancer-specific p53 mutational spectra have been identified. Data from murine models and human BRCA1-related hereditary breast cancers suggest that both unique and specific BRCA1-associated p53 mutations may be found in BRCA1-related ovarian cancers. EXPERIMENTAL DESIGN: The p53 mutational spectrum from ovarian cancers containing either somatic or germ-line BRCA1 mutations was compared with that of...

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Share to BRCA1 Protein
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Neoplasm Staging

Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 11309330

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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