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Article

Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.

Journal of the National Cancer Institute - 3 Jul 2002

Jazaeri Amir A, Yee Cindy J, Sotiriou Christos, Brantley Kelly R, Boyd Jeff, Liu Edison T

Abstract excerpt

BACKGROUND: Germline mutations in BRCA1 and BRCA2 are responsible for 5%-10% of epithelial ovarian cancers, but the molecular pathways affected by these mutations are unknown. We used complementary DNA (cDNA) microarrays to compare gene expression patterns in ovarian cancers associated with BRCA1 or BRCA2 mutations with gene expression patterns in sporadic epithelial ovarian cancers and to identify patterns...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12096084
DOI: 10.1093/jnci/94.13.990

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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