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Article

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

Aging - 1 Dec 2010

Ugalde Alejandro P, Mariño Guillermo, López-Otín Carlos

Abstract excerpt

We have recently reported that progeroid Zmpste24-/- mice, which exhibit multiple defects that phenocopy Hutchinson-Gilford progeria syndrome, show a profound dysregulation of somatotropic axis, mainly characterized by the occurrence of very high circulating levels of growth hormone (GH) and a dr...

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Identifiers

PMID: 21212467
DOI: 10.18632/aging.100262
PMCID: PMC3034170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21212467-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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