Article

Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome

2023-05-02

Abstract excerpt

Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal genetic condition arising from a single nucleotide alteration in the LMNA gene, which leads to the production of a defective lamin A protein known as progerin. The buildup of progerin hastens the onset of premature and expedited aging. Patients with HGPS exhibit short stature, low body weight, lipodystrophy, metabolic dysfunction, and skin and muscul...

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Literature Corpus work: a4a9b2fb-13eb-5bc8-840e-396aa7350611
DOI: 10.1101/2023.05.02.539084

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