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Article

The Use of Multiplicity Corrections, Order Statistics and Generalized Family-Wise Statistics with Application to Genome-Wide Studies.

PloS one - 1 Jan 2016

Schrodi Steven J

Abstract excerpt

The most important decision faced by large-scale studies, such as those presently encountered in human genetics, is to distinguish between those tests that are true positives from those that are not. In the context of genetics, this entails the determination of genetic markers that actually underlie medically-relevant phenotypes from a vast number of makers typically interrogated in genome-wide studies. A...

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PMID: 27128491
DOI: 10.1371/journal.pone.0154472
PMCID: PMC4851310

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