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Article

Modification by the genes ALAD and VDR of lead-induced cognitive effects in children.

Neurotoxicology - 1 Jan 2012

Pawlas Natalia, Broberg Karin, Olewińska Elżbieta, Prokopowicz Adam, Skerfving Staffan, Pawlas Krystyna

Abstract excerpt

Lead has negative effect on cognitive functions in children. However, individuals differ in susceptibility. One possible explanation is a genetic predisposition. Polymorphisms in the δ-aminolevulinic acid dehydratase (ALAD) and the vitamin D receptor (VDR) genes may modify lead metabolism and neurotoxicity, but information regarding the central nervous system is very limited. The aim of the study was to determine...

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Source

Identifiers

PMID: 22101007
DOI: 10.1016/j.neuro.2011.10.012

Genes

ALAD
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Modification by the genes ALAD and VDR of lead-induced cognitive effects in children.PMID 22101007Read ↗

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