[Mutations in the 61st codon of the c-Ki-ras oncogene during transplacental lung tumor induction in mice and their difference in spontaneous and induced tumors].

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Article

[Mutations in the 61st codon of the c-Ki-ras oncogene during transplacental lung tumor induction in mice and their difference in spontaneous and induced tumors].

Molekuliarnaia biologiia - 1 Jan 2000

Loktionov A S

Abstract excerpt

DNA isolated from lung and liver tumor which were induced in CD-1 mice by transplacental treatment with 7,12-dimethylbenz(a)anthracene (DMBA) or developed spontaneously was analyzed for the presence of Ha- and Ki-ras oncogene codon 61 mutations. The A to T transversions at the second position of...

Topics

9,10-Dimethyl-1,2-benzanthracene
Animals
Base Sequence
Codon
Female
Genes, ras
Liver Neoplasms, Experimental
Lung Neoplasms
Maternal-Fetal Exchange
Mice
Molecular Sequence Data
Mutation
Nucleic Acid Hybridization
Pregnancy

Source

Open in PubMed

Identifiers

PMID: 1813798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1813798-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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