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Article

BDNF gene effects on brain circuitry replicated in 455 twins.

NeuroImage - 15 Mar 2011

Chiang Ming-Chang, Barysheva Marina, Toga Arthur W, Medland Sarah E, Hansell Narelle K, James Michael R, McMahon Katie L, de Zubicaray Greig I, Martin Nicholas G, Wright Margaret J, Thompson Paul M

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) plays a key role in learning and memory, but its effects on the fiber architecture of the living brain are unknown. We genotyped 455 healthy adult twins and their non-twin siblings (188 males/267 females; age: 23.7±2.1 years, mean±SD) and scanned them with high angular resolution diffusion tensor imaging (DTI), to assess how the BDNF Val66Met polymorphism affects white...

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Identifiers

PMID: 21195196
DOI: 10.1016/j.neuroimage.2010.12.053
PMCID: PMC3192852

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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