Article
Genes involved in initial follicle recruitment may be associated with age at menopause.
The Journal of clinical endocrinology and metabolism - 1 Mar 2011
Voorhuis Marlies, Broekmans Frank J, Fauser Bart C J M, Onland-Moret N Charlotte, van der Schouw Yvonne T
Abstract excerpt
CONTEXT: Timing of menopause is largely influenced by genetic factors. Because menopause occurs when the follicle pool in the ovaries has become exhausted, genes involved in primordial follicle recruitment can be considered as candidate genes for timing of menopause. OBJECTIVE: The aim was to study the association of 23 tagging single nucleotide polymorphisms in five genes [Anti-Müllerian hormone (AMH), AMH type...
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