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Candidate genes for age at menarche are associated with endometrial hyperplasia.

Gene - 5 Oct 2020

Ponomarenko Irina, Reshetnikov Evgeny, Polonikov Alexey, Sorokina Inna, Yermachenko Anna, Dvornyk Volodymyr, Churnosov Mikhail

Abstract excerpt

OBJECTIVES: To study associations candidate genes for age at menarche with a risk of endometrial hyperplasia (EH). METHODS: 52 candidate loci for age at menarche were analyzed for possible association with EH in a sample of 520 patients and 981 controls. Association of the polymorphisms was analyzed using the method of logistic regression. The gene-gene and gene-environment interactions were analyzed using...

Topics

Adult
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Endometrial Hyperplasia
Female
Follicle Stimulating Hormone, beta Subunit
Gene-Environment Interaction
Humans
Menarche
Middle Aged
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, LH

Source

Identifiers

PMID: 32640302
DOI: 10.1016/j.gene.2020.144933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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