Article
Interactions between genetic variants in AMH and AMHR2 may modify age at natural menopause.
PloS one - 1 Jan 2013
Braem Marieke G M, Voorhuis Marlies, van der Schouw Yvonne T, Peeters Petra H M, Schouten Leo J, Eijkemans Marinus J C, Broekmans Frank J, Onland-Moret N Charlotte
Abstract excerpt
The onset of menopause has important implications on women's fertility and health. We previously identified genetic variants in genes involved in initial follicle recruitment as potential modifiers of age at natural menopause. The objective of this study was to extend our previous study, by searching for pairwise interactions between tagging single nucleotide polymorphisms (tSNPs) in the 5 genes previously...
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