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Article

Novel and nondetected human signaling protein polymorphisms.

Physiological genomics - 3 Sept 2002

Lynch Roy A, Wagoner Lynne, Li Shunan, Sparks Li, Molkentin Jeffery, Dorn Gerald W

Abstract excerpt

The frequency of single nucleotide polymorphisms (SNPs) in downstream signaling proteins was determined by combination heteroduplex HPLC and double-stranded sequencing of genomic DNA from 96-144 congestive heart failure (CHF) patients. Analysis of 56 coding exons in 9 signaling genes revealed 17 novel and 8 previously reported synonymous (no change in amino acid) SNPs, as well as one novel nonsynonymous SNP in...

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PMID: 12209018
DOI: 10.1152/physiolgenomics.00030.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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