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Article

The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time--an ultra-deep approach.

PLoS computational biology - 16 Dec 2010

Archer John, Rambaut Andrew, Taillon Bruce E, Harrigan P Richard, Lewis Marilyn, Robertson David L

Abstract excerpt

Large-scale parallel pyrosequencing produces unprecedented quantities of sequence data. However, when generated from viral populations current mapping software is inadequate for dealing with the high levels of variation present, resulting in the potential for biased data loss. In order to apply t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21187908
DOI: 10.1371/journal.pcbi.1001022
PMCID: PMC3002995

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21187908-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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