Article
Genome-wide linkage analysis for uric acid in families enriched for hypertension.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Aug 2009
Rule Andrew D, Fridley Brooke L, Hunt Steven C, Asmann Yan, Boerwinkle Eric, Pankow James S, Mosley Thomas H, Turner Stephen T
Abstract excerpt
BACKGROUND: Uric acid is heritable and associated with hypertension and insulin resistance. We sought to identify genomic regions influencing serum uric acid in families in which two or more siblings had hypertension. METHODS: Uric acid levels and microsatellite markers were assayed in the Genetic Epidemiology Network of Arteriopathy (GENOA) cohort (1075 whites and 1333 blacks) and the Hypertension Genetic...
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