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Article

Activity-guided engineering of natural product carrier proteins.

Molecular bioSystems - 1 Feb 2011

Worthington Andrew S, Hur Gene H, Burkart Michael D

Abstract excerpt

A panel of chimeric carrier proteins was developed and screened for functional activity with essential enzymes involved in carrier protein-mediated biosynthesis. Regions on either side of the recognition helix II within three carrier proteins (CPs) from distinct biosynthetic pathways were swapped in all combinations to generate 24 mutated CPs. This panel of chimeric carrier proteins was tested using two...

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Identifiers

PMID: 21184004
DOI: 10.1039/c0mb00251h
PMCID: PMC12888839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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