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Article

Advances in directed protein evolution by recursive genetic recombination: applications to therapeutic proteins.

Current opinion in biotechnology - 1 Aug 2001

Kurtzman A L, Govindarajan S, Vahle K, Jones J T, Heinrichs V, Patten P A

Abstract excerpt

Recent developments in directed evolution technologies combined with innovations in robotics and screening methods have revolutionized protein engineering. These methods are being applied broadly to many fields of biotechnology, including chemical engineering, agriculture and human therapeutics. More specifically, DNA shuffling and other methods of genetic recombination and mutation have resulted in the...

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Identifiers

PMID: 11551464
DOI: 10.1016/s0958-1669(00)00228-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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