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Article

A chemical toolkit for proteins--an expanded genetic code.

Nature reviews. Molecular cell biology - 1 Oct 2006

Xie Jianming, Schultz Peter G

Abstract excerpt

Recently, a method to encode unnatural amino acids with diverse physicochemical and biological properties genetically in bacteria, yeast and mammalian cells was developed. Over 30 unnatural amino acids have been co-translationally incorporated into proteins with high fidelity and efficiency using a unique codon and corresponding transfer-RNA:aminoacyl-tRNA-synthetase pair. This provides a powerful tool for...

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Identifiers

PMID: 16926858
DOI: 10.1038/nrm2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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