Article
Placental growth factor induces FosB and c-Fos gene expression via Flt-1 receptors.
FEBS letters - 16 Jan 2004
Holmes David I R, Zachary Ian
Abstract excerpt
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family that binds specifically to Flt-1. The biological roles of PlGF and Flt-1 have not yet been defined and the signalling mechanisms mediating cellular actions of PlGF remain poorly understood. In human umbilical vein endothelial cells, VEGF and PlGF induced expression of both full-length FosB mRNA and an alternatively...
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