Article
Regulation of the glucocorticoid receptor gene by the AP-1 transcription factor.
Endocrine - 1 Dec 1997
Wei P, Vedeckis W V
Abstract excerpt
The glucocorticoid receptor (GR) is a ligand-activated nuclear transcription factor, and AP- 1 (Fos/Jun or Jun/Jun) is a transcription factor whose components are nuclear proteins encoded by c-fos and c-jun protooncogenes. Serum stimulation of serum-starved NIH 3T3 cells resulted in an approx 188...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Blotting, Western
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation
- Humans
- Luciferases
- Mice
- Mutation
- Plasmids
- Proto-Oncogene Proteins c-fos
- Proto-Oncogene Proteins c-jun
- RNA, Messenger
- Receptors, Glucocorticoid
- Ribonucleases
- Transcription Factor AP-1
- Transfection
