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Article

Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.

ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2004

Kureshi Nelofar, Ghaffar Shehzad, Siddiqui Sammer, Salahuddin Iftikhar, Frossard Philippe M

Abstract excerpt

Progress in the elucidation of molecular genetic changes that lead to the development of tumors should soon bring novel diagnostic and therapeutic procedures into clinical practice. In this respect, methylenetetrahydrofolate reductase (MTHFR) plays a central role in folate metabolism that affects DNA methylation and synthesis. DNA methylation is an epigenetic feature that influences cellular development and...

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Source

Identifiers

PMID: 15583437
DOI: 10.1159/000081120

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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