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Article

An SP1-binding site polymorphism in the COLIAI gene and osteoporosis in Egyptian patients with thalassemia major.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2011

Hamed Hanan M, Galal Ashraf, Ghamrawy Mona E L, Abd El Azeem Khaled, Hussein Ibtessam Ramzi, Abd-Elgawad Mona Fayez

Abstract excerpt

β-Thalassemia major is an inherited blood disorder, which mainly affects the Mediterranean region. Osteoporosis represents an important cause of morbidity in β-thalassemia major and its pathogenesis has not been completely clarified. Genetic factors play an important role in the pathogenesis of osteoporosis and several candidate gene polymorphisms have been implicated in the regulation of this process. A G→T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21178584
DOI: 10.1097/MBC.0b013e32834248fb

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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