Article
Bone mineral density in young women of the city of São Paulo, Brazil: correlation with both collagen type I alpha 1 gene polymorphism and clinical aspects.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Aug 2002
Barros E R, Kasamatsu T S, Ramalho A C, Hauache O M, Vieira J G H, Lazaretti-Castro M
Abstract excerpt
Osteoporosis is a multifactorial disease with great impact on morbidity and mortality mainly in postmenopausal women. Although it is recognized that factors related to life-style and habits may influence bone mass formation leading to greater or lower bone mass, more than 85% of the variation in bone mineral density (BMD) is genetically determined. The collagen type I alpha 1 (COLIA1) gene is a possible risk...
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