Article
Gene polymorphisms involved in the regulation of bone quality.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Mar 2006
Thijssen Jos H H
Abstract excerpt
Osteoporotic fractures in subjects at advanced age constitute a tremendous and growing problem. Established lifestyle risk factors can explain only a modest proportion of the liability to osteoporotic fractures. Bone mineral density (BMD) is considered the best established risk factor for osteoporotic fractures. The importance of genetic factors in the quality of bone is substantial, but no consensus exists yet...
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