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Article

Ethnic difference in contribution of Sp1 site variation of COLIA1 gene in genetic predisposition to osteoporosis.

Calcified tissue international - 1 Nov 1999

Nakajima T, Ota N, Shirai Y, Hata A, Yoshida H, Suzuki T, Hosoi T, Orimo H, Emi M

Abstract excerpt

Osteoporosis, a condition characterized by low bone mineral density (BMD) leading to bone fragility [1], is a major public health concern in Japan as well as in other countries. Although genetic predisposition seems to be a factor in the pathogenesis of osteoporosis [2-4], the precise cohort of genes that may be involved is not well defined. The COLIA1 and COLIA2 genes encode polypeptide constituents of collagen...

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Source

Identifiers

PMID: 10541758
DOI: 10.1007/s002239900711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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