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Article

Evolutionarily conserved, growth plate zone-specific regulation of the matrilin-1 promoter: L-Sox5/Sox6 and Nfi factors bound near TATA finely tune activation by Sox9.

Molecular and cellular biology - 1 Feb 2011

Nagy Andrea, Kénesi Erzsébet, Rentsendorj Otgonchimeg, Molnár Annamária, Szénási Tibor, Sinkó Ildikó, Zvara Agnes, Oommen Sajit Thottathil, Barta Endre, Puskás László G, Lefebvre Veronique, Kiss Ibolya

Abstract excerpt

To help uncover the mechanisms underlying the staggered expression of cartilage-specific genes in the growth plate, we dissected the transcriptional mechanisms driving expression of the matrilin-1 gene (Matn1). We show that a unique assembly of evolutionarily conserved cis-acting elements in the...

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Identifiers

PMID: 21173167
DOI: 10.1128/MCB.00019-10
PMCID: PMC3028657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21173167-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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