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Chondrocyte-specific Enhancer Elements in the Col11a2 Gene Resemble the Col2a1 Tissue-specific Enhancer

1 Jun 1998

Abstract excerpt

Type XI collagen and type II collagen are coexpressed in all cartilage, and both are essential for normal cartilage differentiation and skeletal morphogenesis. This laboratory has recently identified a 48-base pair (bp) enhancer element in the type II collagen gene Col2a1 that contains several HMG-type protein-binding sites and that can direct chondrocyte-specific expression in transient transfection and in...

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Identifiers

PMID: 9614107
DOI: 10.1074/jbc.273.24.14998

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Related research

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Research trail→

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Chondrocyte-specific Enhancer Elements in the Col11a2 Gene Resemble the Col2a1 Tissue-specific EnhancerPMID 9614107Read ↗

Different cis-Regulatory DNA Elements Mediate Developmental Stage- and Tissue-specific Expression of the Human COL2A1 Gene in Transgenic MiceSemantic proximity Read ↗

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Expression Profiling and Functional Analysis of Candidate Col10a1 Regulators Identified by the TRAP ProgramSemantic proximity Read ↗

Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiationSemantic proximity Read ↗

The new collagen gene COL27A1 contains SOX9-responsive enhancer elements.Semantic proximity Read ↗

Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer.Semantic proximity Read ↗

Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human α2(I) Collagen (COL1A2) GeneSemantic proximity Read ↗

Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte–specific expression in vivoSemantic proximity Read ↗

Chondrogenic Enhancer Landscape of Limb and Axial Skeleton DevelopmentSemantic proximity Read ↗

Regulation of Human COL2A1 Gene Expression in ChondrocytesSemantic proximity Read ↗

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