Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.

Mechanisms of development - 1 Nov 2000

Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann B G

Abstract excerpt

We have adapted the whole-mount in situ hybridization technique to perform high-throughput gene expression analysis in mouse embryos. A large-scale screen for genes showing specific expression patterns in the mid-gestation embryo was carried out, and a large number of genes controlling development were isolated. From 35760 clones of a 9.5 d.p.c. cDNA library, a total of 5348 cDNAs, enriched for rare transcripts,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Embryonic and Fetal Development

Share to Gene Expression Regulation, Developmental

Share to Genetic Testing

Share to In Situ Hybridization

Source

Identifiers

PMID: 11044609
DOI: 10.1016/s0925-4773(00)00453-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.PMID 11044609Read ↗

Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis.Semantic proximity Read ↗

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.Semantic proximity Read ↗

Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse developmentSemantic proximity Read ↗

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarraySemantic proximity Read ↗

Differences in Gene Expression between Mouse and Human for Dynamically Regulated Genes in Early EmbryoSemantic proximity Read ↗

Molecular processes during fat cell development revealed by gene expression profiling and functional annotation.Semantic proximity Read ↗

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis.Semantic proximity Read ↗

Pathology methods for the evaluation of embryonic and perinatal developmental defects and lethality in genetically engineered mice.Semantic proximity Read ↗

Embryonic gene transcription in the spiny mouse ( <i>Acomys cahirinus</i> ): an investigtion into the embryonic genome activationSemantic proximity Read ↗

Cloning of full-length cDNA sequence of a novel candidate gene related to mouse cleft palate.Semantic proximity Read ↗

An inducible RNA interference system for the functional dissection of mouse embryogenesis.Semantic proximity Read ↗

Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.