Article
Enhanced GDNF expression in dopaminergic cells of monkeys grafted with carotid body cell aggregates.
Brain research - 23 Feb 2011
Luquin M R, Manrique M, Guillén J, Arbizu J, Ordoñez C, Marcilla I
Abstract excerpt
Striatal carotid body cell aggregates (CBCA) grafts improve parkinsonism in animals and patients with Parkinson's disease. As CB cells contain trophic factors, we investigated the long-term effect of striatal CBCA grafts on nigrostriatal dopaminergic cells in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkeys receiving unilateral (UL-grafted group, n=4) or bilateral (BL-grafted group, n=3) CBCA...
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