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Article

Intrastriatal Grafting of Chromospheres: Survival and Functional Effects in the 6-OHDA Rat Model of Parkinson's Disease.

PloS one - 1 Jan 2016

Boronat-García Alejandra, Palomero-Rivero Marcela, Guerra-Crespo Magdalena, Millán-Aldaco Diana, Drucker-Colín René

Abstract excerpt

Cell replacement therapy in Parkinson's disease (PD) aims at re-establishing dopamine neurotransmission in the striatum by grafting dopamine-releasing cells. Chromaffin cell (CC) grafts produce some transitory improvements of functional motor deficits in PD animal models, and have the advantage of allowing autologous transplantation. However, CC grafts have exhibited low survival, poor functional effects and...

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Identifiers

PMID: 27525967
DOI: 10.1371/journal.pone.0160854
PMCID: PMC4985142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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