Article
Transplantation of Human Neural Stem Cells in a Parkinsonian Model Exerts Neuroprotection via Regulation of the Host Microenvironment.
International journal of molecular sciences - 5 Nov 2015
Zuo Fu-Xing, Bao Xin-Jie, Sun Xi-Cai, Wu Jun, Bai Qing-Ran, Chen Guo, Li Xue-Yuan, Zhou Qiang-Yi, Yang Yuan-Fan, Shen Qin, Wang Ren-Zhi
Abstract excerpt
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons and consequent dopamine (DA) deficit, and current treatment still remains a challenge. Although neural stem cells (NSCs) have been evaluated as appealing graft sources, mechanisms underlying the beneficial phenomena are not well understood. Here, we investigate whether human NSCs (hNSCs) transplantation could provide...
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