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Article

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo.

Neuron - 1 Dec 1995

Arenas E, Trupp M, Akerud P, Ibáñez C F

Abstract excerpt

The locus coeruleus (LC), the main noradrenergic center in the brain, participates in many neural functions, as diverse as memory and motor output, and is severely affected in several neurodegenerative disorders of the CNS. GDNF, a neurotrophic factor initially identified as dopaminotrophic, was found to be expressed in several targets of central noradrenergic neurons in the adult rat brain. Grafting of...

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Identifiers

PMID: 8845169
DOI: 10.1016/0896-6273(95)90024-1

Genes

GDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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