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Article

Association between late-onset Alzheimer's disease and microsatellite polymorphisms in intron II of the human toll-like receptor 2 gene.

Neuroscience letters - 11 Feb 2011

Wang Li-Zhu, Tian Yan, Yu Jin-Tai, Chen Wei, Wu Zhong-Chen, Zhang Qun, Zhang Wei, Tan Lan

Abstract excerpt

The amyloid beta protein (Aβ) deposits in the brains of patients with Alzheimer's disease (AD) are closely associated with innate immune responses that were assumed to play a pivotal role in the pathogenesis of AD. Toll-like receptor 2 (TLR2) is thought to contribute to Aβ clearance. Studies have...

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Source

Identifiers

PMID: 21163333
DOI: 10.1016/j.neulet.2010.12.008

Genes

TLR2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21163333-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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