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Article

Toll-like receptors in Alzheimer's disease.

Journal of neuroimmunology - 15 Nov 2020

Momtazmanesh Sara, Perry George, Rezaei Nima

Abstract excerpt

Neuroinflammation and microglial dysfunction are key contributors to the development of Alzheimer's disease (AD). Toll-like receptors (TLRs) are transmembrane proteins primarily involved in immune responses and expressed by several immune and non-immune cells within the central nervous system. Signaling of TLRs affects the core of AD changes, including synaptic plasticity, microglial activity, tau...

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Identifiers

PMID: 32858428
DOI: 10.1016/j.jneuroim.2020.577362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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