Article
Cellular and molecular characteristics of transformed T cells from an antigen-specific T-cell line.
Scandinavian journal of immunology - 1 May 1990
Wegener A M, Holm B, Geisler C, Rubin B
Abstract excerpt
An antigen-specific T-cell line which transforms into T-lymphoma cells in vitro but apparently not in vivo is described. Membrane markers, tumorigenicity and T-cell receptor (TcR) V alpha and V beta-gene usage of the in vitro transformed T-cell line were analysed to investigate whether the transformation event was poly-, oligo-, or monoclonal. The results indicate that the T lymphoma has no chromosome...
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