Article
Production of mouse monoclonal antibodies against human HLA-A3 for use in microlymphocytotoxicity technique.
Human antibodies - 1 Jan 2009
Yari Fatemeh, Sareh Shahla, Sadri Azadeh, Sharifi Zohreh, Najafi Freshteh
Abstract excerpt
Monoclonal antibody production using the hybridoma technology is one of the attractive areas of research. The aim of this study was to investigate the production of monoclonal antibodies to human HLA-A3 antigen for use in microlymphocytotoxicity technique. HLA-A3 antigen was purified from human leukocytes and injected to several mice. The spleen-derived cells of immunized animal were fused with P3-X63-Ag8 myeloma...
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