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Article

The glypican 3-hosted murine mir717 gene: sequence conservation, seed region polymorphisms and putative targets.

International journal of biological sciences - 2 Dec 2010

Kunej Tanja, Skok Dasa Jevsinek, Horvat Simon, Dovc Peter, Jiang Zhihua

Abstract excerpt

Mir717 (mmu-mir-717) was first reported in mouse and resides in the intron 3 of glypican 3 (Gpc3) gene. Our present study revealed that this microRNA (miRNA) gene is conserved among 26 mammalian species and harbors polymorphic sites within the mature seed region in mice. Our finding represents a rare four layer genomic overlap consisting of growth associated quantitative trait locus (QTL), body mass associated...

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Identifiers

PMID: 21152117
DOI: 10.7150/ijbs.6.769
PMCID: PMC2999852

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Source receipt: pubmed, retrieved 7 Sept 2026.

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