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Article

Genetic variants and haplotype structures of miRNA host genes in cancer and obesity.

Journal of biomolecular structure & dynamics - 1 Apr 2025

Gholami Morteza

Abstract excerpt

Cancer and obesity are two important public health problems. This study aimed to investigate the role of genetic variants and haplotypes of miRNA host genes in cancer and obesity. Data from the catalog of genome-wide association studies (GWAS) were used to find significant variants (index). Then, 1000-genome phase 3 data were used to find haplotypic variants (proxy) associated with these diseases. The candidate...

Read the complete abstract on PubMed

Topics

Humans
MicroRNAs
Haplotypes
Obesity
Polymorphism, Single Nucleotide
Genome-Wide Association Study
Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genetic Variation

Female

Source

Identifiers

PMID: 38174558
DOI: 10.1080/07391102.2023.2300056

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