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Article

Genetic variations in IKZF3, LET7-a2, and CDKN2B-AS1: Exploring associations with metabolic syndrome susceptibility and clinical manifestations.

Journal of clinical laboratory analysis - 1 Jan 2024

Paniri Alireza, Hosseini Mohammad Mahdi, Fattahi Sadegh, Amiribozorgi Galia, Asouri Mohsen, Maadi Mansooreh, Motamed Nima, Zamani Farhad, Akhavan-Niaki Haleh

Abstract excerpt

BACKGROUND AND AIM: Metabolic syndrome (MetS) increases the risk of atherosclerosis and diabetes, but there are no approved predictive markers. This study assessed the role of specific genetic variations in MetS susceptibility and their impact on clinical manifestations. METHOD: In this study, a genotype-phenotype assessment was performed for IKZF3 (rs907091), microRNA-let-7a-2 (rs1143770), and lncRNA-CDKN2B-AS1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38193570
DOI: 10.1002/jcla.24999
PMCID: PMC10829692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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