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Article

Association of HLA-B*5701 genotypes and abacavir-induced hypersensitivity reaction: a systematic review and meta-analysis.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques - 1 Jan 2015

Tangamornsuksan Wimonchat, Lohitnavy Ornrat, Kongkaew Chuenjid, Chaiyakunapruk Nathorn, Reisfeld Brad, Scholfield Norman Charles, Lohitnavy Manupat

Abstract excerpt

OBJECTIVES: This study aimed to systematically review and quantitatively synthesize the association between HLA-B*5701 and abacavir-induced hypersensitivity reaction (ABC-HSR). METHODS: We searched for studies that investigated the association between HLA-B genotype and ABC-HSR and provided information about the frequency of carriers of HLA-B genotypes among cases and controls. We then performed a meta-analysis...

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PMID: 25877443
DOI: 10.18433/j39s3t

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