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Article

[HLA-B*5701 and abacavir hypersensitivity reaction].

Pathologie-biologie - 1 Dec 2010

Servonnet A, Leclercq E, Delacour H, Ceppa F

Abstract excerpt

A potentially life-threatening hypersensitive reaction occurs in association with initiation of HIV nucleoside analogue abacavir therapy in 4 to 8% of patients. Preliminary studies appear to confirm the role of the immune system in abacavir hypersensitivity. The reaction is possibly the result of presentation of drug peptides onto HLA, that may induce a pathogenic T-cell response. Hypersensitivity reaction to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19243901
DOI: 10.1016/j.patbio.2008.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[HLA-B*5701 and abacavir hypersensitivity reaction].PMID 19243901Read ↗

[Correlation, in previously treated HIV-1 positive patients, between hypersensitivity reaction to abacavir and the presence of the HLA-B*5701 allele].Semantic proximity Read ↗

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HLA-B*5701 testing to predict abacavir hypersensitivitySemantic proximity Read ↗

Abacavir adverse reactions related with HLA-B*57: 01 haplotype in a large cohort of patients infected with HIV.Semantic proximity Read ↗

ASSOCIATION BETWEEN PRESENCE OF HLA-B*5701, HLA-DR7, AND HLA-DQ3 AND HYPERSENSITIVITY TO HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR ABACAVIRSemantic proximity Read ↗

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