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Article

[HLA-B*5701 and hypersensitivity reactions to abacavir. Study methods and clinical relevance].

Enfermedades infecciosas y microbiologia clinica - 1 May 2008

Arnedo Valero Mireia

Abstract excerpt

Hypersensitivity reactions to abacavir occur in 5-8% of patients starting treatment with this drug and limits future treatment. Some host genetic factors, especially the HLA-B*5701 allele, have been identified as risk factors for hypersensitivity reaction in Caucasians. Consequently, the possibility of routine implementation of a genetic test to rule out the presence of this allele has been proposed to achieve a...

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Identifiers

PMID: 18680694
DOI: 10.1016/s0213-005x(08)76510-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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