Article
FKS2 mutations associated with decreased echinocandin susceptibility of Candida glabrata following anidulafungin therapy.
Antimicrobial agents and chemotherapy - 1 Mar 2011
Costa-de-Oliveira Sofia, Marcos Miranda Isabel, Silva Raquel M, Pinto E Silva Ana, Rocha Rita, Amorim António, Gonçalves Rodrigues Acácio, Pina-Vaz Cidália
Abstract excerpt
This is the first case report of Candida glabrata-disseminated candidiasis describing the acquisition of echinocandin resistance following anidulafungin treatment. The initial isolates recovered were susceptible to echinocandins. However, during 27 days of anidulafungin treatment, two resistant strains were isolated (from the blood and peritoneal fluid). The resistant peritoneal fluid isolate exhibited a...
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